|
KMID : 0363120150280030198
|
|
Korean Journal of Pain
2015 Volume.28 No. 3 p.198 ~ p.202
|
|
|
Effect of Intravenous Intraoperative Esmolol on Pain Management Following Lower Limb Orthopedic Surgery
|
|
Haghighi Mohammad
Sedighinejad Abbas
Mirbolook Ahmadreza
Nabi Bahram Naderi
Farahmand Maral
leili Ehsan Kazemnez
Shirvani Masoumeh
Jahromi Sina Khajeh
|
|
|
Abstract
|
|
|
Background: Lack of proper control of acute postoperative pain often leads to lingering or chronic pain. Several studies have emphasized the role of beta-blockers in reducing postoperative pain. Esmolol is a selective short-acting beta-blocker that produces few side effects. The purpose of this study was to examine the effect of intravenous intraoperative esmolol on postoperative pain reduction following orthopedic leg fracture surgery.
Methods: In a clinical trial, 82 patients between 20?65 years of age with tibia fractures and American Society of Anesthesiologists (ASA) physical status I & II who underwent surgery were divided into two groups. Group A received esmolol and group B received normal saline. Postoperative pain was measured at three time points: entering the recovery unit, and at 3 h and 6 h following surgery, using the Visual Analogue Scale (VAS). A P value of ＜ 0.05 was considered significant.
Results: Mean VAS scores at all three time points were significantly different between the two test groups (P = 0.02, P = 0.0001, and P = 0.0001, respectively). The consumption of pethidine was lower in group A than in group B (P = 0.004) and the duration of its effect was significantly longer in time (P = 0.026).
Conclusions: Intravenous intraoperative esmolol is effective in the reduction of postoperative pain following leg fracture surgery. It reduced opioid consumption following surgery and delayed patient requests for analgesics.
|
|
|
KEYWORD
|
|
|
Esmolol, Meperidine, Orthopedic surgery, Pain management, Pain measurement, Postoperative pain, Tibial fractures, Visual analog scale
|
|
|
FullTexts / Linksout information
|
|
|
|
|
Listed journal information
|
|
   
|